Aminosalicylic acid
Granupas, Neopasalate, Para-aminosalicylic Acid, Parasal, Paser, Rezipas (aminosalicylic acid) is a small molecule pharmaceutical. Aminosalicylic acid was first approved as Parasal sodium on 1982-01-01. It is used to treat crohn disease and tuberculosis in the USA. It has been approved in Europe to treat tuberculosis. The pharmaceutical is active against peroxisome proliferator-activated receptor gamma.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| infections | D007239 |
| digestive system diseases | D004066 |
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
— A07: Antidiarrheals, intestinal antiinflammatory/antiinfective agents
— A07E: Intestinal antiinflammatory agents
— A07EC: Aminosalicylic acid and similar agents
J: Antiinfectives for systemic use
— J04: Antimycobacterials
— J04A: Drugs for treatment of tuberculosis
— J04AA: Aminosalicylic acid and derivatives
— J04AA01: 4-aminosalicylic acid
HCPCS
No data
Clinical
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Drug
General
| Drug common name | Aminosalicylic acid |
| INN | — |
| Description | 4-aminosalicylic acid is an aminobenzoic acid that is salicylic acid substituted by an amino group at position 4. It has a role as an antitubercular agent. It is an aminobenzoic acid and a member of phenols. It is functionally related to a salicylic acid. It is a conjugate acid of a 4-aminosalicylate(1-). |
| Classification | Small molecule |
| Drug class | anti-inflammatory agents (salicylic acid derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Nc1ccc(C(=O)O)c(O)c1 |
Identifiers
| PDB | — |
| CAS-ID | 65-49-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1169 |
| ChEBI ID | 27565 |
| PubChem CID | 4649 |
| DrugBank | DB00233 |
| UNII ID | — |
Target
Agency Approved
PPARG
PPARG
Organism
Homo sapiens
Gene name
PPARG
Gene synonyms
NR1C3
NCBI Gene ID
Protein name
peroxisome proliferator-activated receptor gamma
Protein synonyms
Nuclear receptor subfamily 1 group C member 3, peroxisome proliferator-activated receptor-gamma 5, peroxisome proliferator-activated receptor-gamma splicing, PPAR-gamma
Uniprot ID
Mouse ortholog
Pparg (19016)
peroxisome proliferator-activated receptor gamma (P37238)
Alternate
No data
Variants
No data
Financial
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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